Clemens Posten

Prof. Clemens Posten

Institute for Bio-Und Lebensmitteltechnik
The University of Karlsruhe, Germany
Phone: +49 721 608 2410
Fax: +49 721 608 7553
Email: [email protected]

Publications

2009

Beckmann, J., Lehr, F., Finazzi, G., Hankamer, B., Posten, C., Wobbe, L. & Kruse, O. (2009).  Improvement of light to biomass conversion by de-regulation of light harvesting protein translation in C. reinhardtii. J. Biotech. In press Ms. Ref. No.:  JBIOTEC-D-08-01071R1. Accepted 17-Feb-2009.

Käppler, T., Cerff, M., Ottow, K.Hobley, T. and Posten, C. (2009). In Situ Magnetic Separation for Extracellular Protein Production. Biotechnology and Bioengineering. 102: 535-545.

Krumov, N., Perner-Nochta, I., Oder, S., Gotcheva, V., Angelov, A., Posten, C. Production of Inorganic Nanoparticles by Microorganisms. Chemical Engineering & Technology, 2009. 32(7), 1026-1035.

Lehr, F., Posten, C. Closed photo-bioreactors as tools for biofuel production. Current Opinion in Biotechnology, 2009. 20, 280-285.

Perner-Nochta, I., Krumov, N., Oder, S., Angelov, A., Posten, C. Biopartikel: Eine Alternative zur Produktion nanoskaliger anorganischer Partikel. Chem-Ing-Tech, 2009. 81(6), 13.

Posten, C. Design principles of photo-bioreactors for cultivation of microalgae. Engineering in Life Sciences, 2009. 9(3), 145-177.

Posten, C., Schaub, G. Microalgae and terrestrial biomass as source for fuels - A process view. J Biotechnol, 2009. 142, 64-69.

2008

Käppler, T., Hickstein, B., Peuker, U. and Posten, C. (2008). Characterization of Magnetic Ion-Exchange Composites for Protein Separation from Biosuspensions. Journal of Bioscience and Bioengineering. 105(6): 111-999. (IF= 1.8)

Schenk, P., Thomas-Hall, S., Stevens, E., Marx, U., Mussgnug, J., Posten, C., Kruse, O. & Hankamer, B. (2008). Second Generation Biofuels: High-efficiency microalgae for biodiesel production. Bioenergy Research 1: 20-43 (IF= NA)

2007

Fleck-Schneider, P., Lehr, F. and Posten, C. (2007) Modelling of growth and product formation of Porphyridium purpureum. 132: 134-141.

Hankamer, B., Lehr, F., Rupprecht, J., Mussgnug, J. H., Posten, C. and Kruse, O. (2007). Photosynthetic biomass and H2 production by green algae: From bioengineering to bioreactor scale up. Physiol Plant 131: 10-21 (IF=2.2)

Hickstein, B., T. Käppler, et al. (2007) Superparamagnetische Funktionspartikel zum Einsatz in der Bioseparation. ProcessNet- Jahrestagung, Aachen.

Käppler, T. and C. Posten (2007) Fractionation of proteins with two-sided electro-ultrafiltration. Journal of Biotechnology 128: 895-907.

Krumov, N., S. Oder, et al. (2007) Accumulation of CdS nanoparticles by yeasts in a fed-batch bioprocess. J. Biotechnology: in print.

Lehr, F. and C. Posten (2007) Modelling of micro-algae growth and product formation based on an optimisation approach. J. Biotechnology in print.

Lucumi, A., C. Posten, et al. (2007) Improved Image Analysis Based Morphological Control Of Recombinant Moss In Photo-Bioreactors. 10th International Symposium on Computer Applications in Biotechnology, Cancun, Mexico, IFAC.

Perner-Nochta, I., A. Lucumi, et al. (2007) Photoautotrophic Cell and Tissue Culture in a Tubular Photobioreactor. Eng. Life Sci. 7(2): 127-135.

Perner-Nochta, I. and Posten, C. (2007) Simluations of light intensity variation in photobioreactors. Journal of Biotechnology 131: 276-285.

Rosello Sastre, R., P. Fleck, et al. (2007) Model based scale-down of photo-bioreactors - a conceptual approach -. J. Biotechnology 132: 127-133.

2006

Fleck-Schneider, P. and C. Posten (2006) Mathematical Model of Microalgae. 6 European Symposium on Biochemical Engineering Science, Salzburg.

Fleck-Schneider, P. and C. Posten (2006) Modelling of the microalga Porphyridium purpureum. 6th European Symposium on Biochemical Engineering Science, Salzburg.

Hofmann, R., T. Käppler, et al. (2006) Pilot-scale presselectrofiltration of biopolymers. Separation and Purification Technology 51: 303-309.

Käppler, T., R. Hofmann, et al. (2006) Elektrofiltration - Einsatzgebiet Enzymproduktion." Chemie Ingenieur Technik 78(3): 261-266.

Lucumi, A. and C. Posten (2006) Establishment of long-term perfusion cultures of recombinant moss in a pilot tubular photobioreactor. Process Biochemistry 41(10): 2180-2187.

Rosello Sastre, R., P. Fleck-Schneider, et al. (2006) Die Funktion der Polysaccharide der Mikroalge P. purpureum in ihrer Produktionskinetik. 24. DECHEMA-Jahrestagung der Biotechnologen, Wiesbaden, Chemie Ingenieur Technik.

2005

Deseniss, S., U. Förter-Barth, et al. (2005) Keramische Mikrobauteile mit mikro-und nanoporösen Strukturen aus biogenen Partikeln. Chemie Ingenieur Technik 77(3): 230-234.

Hoff, B., E. Strandberg, et al. (2005) H-2-NMR study and molecular dynamics simulation of the location, alignment, and mobility of pyrene in POPC bilayers. Biophysical Journal 88(3): 1818-1827.

Käppler, T., R. Hofmann, et al. (2005) Fractionation of Biopolymers and Biosuspensions with Pressure Electrofiltration. 18th Annual Conference, Atlanta, USA, American Filtration and Separation Society.

Käppler, T., R. Hofmann, et al. (2005) Fractionation of biopolymers and biosuspensions with pressure electrofiltration. FILTECH, Wiesbaden, GVT.

Lucumi, A., C. Posten, et al. (2005) Image Analysis Supported Moss Cell Disruption in Photo-Bioreactors. Plant Biology 7(3): 276-282.

Lucumi, A. and C. Posten (2005) Moose als Expressionssystem glycosylierter rekombinanter Proteine in einem Pilot-Rohr-Photobioreaktor. GVC Jahrestagung, Wiesbaden, GVC.

Lucumi, A. and C. Posten (2005) Moss cells in photobioreactors, a promising expression system for glycosylated proteins. J. Biotechnology 118(S1): 68.

Posten, C., M. Herrenbauer, et al. (2005) Electric Field Pressure Filtration of Biopolymers. EU-Patent.

Posten, C. (2005) Bioprocess Engineering "bio-ag" of the Institute of Mechanical Process Engineering at the University of Karlsruhe. Ecological Engineering and Environment Protection 4(1): 52-58.

Saveyn, H., P. v. d. Meeren, et al. (2005) Modelling two-sided electrofiltration of quartz suspensions: Importance of electrochemical reactions. Chemical Engineering Science 60: 6768-6779.

2004

Deseniss, S. and C. Posten (2004) Gewinnung mikrobiell gebildeter Nanopartikel unter Verwendung schwermetallbelasteter Abwässer. GVC Jahrestagung, Karlsruhe, Germany, GVC.

Fleck, P. and C. Posten (2004) Modelling of growth and product formation of Porphyridium purpureum under defined conditions. Computer Applications in Biotechnology, CAB9, Nancy, France.

Göttel, M., C. Posten, et al. (2004) Hydrogen Production by Anaerobic Dark Digestion of Waste and Wastewater. Auftragsstudie für EnBW. Karlsruhe: 62.

Hoff, B., M. Herrenbauer, et al. (2004) Molekulardynamische Simulation zu Verhalten und Wirkung polycyclischer aromatischer Kohlenwasserstoffe (PAK) in Phospholipid-Membranen. Chemie Ingenieur Technik 76(7): 1017-1021.

Mironescu, M., M. Ignatova, et al. (2004) Optimal glucise feeding profile application in Haloferax mediterranei fed-batch cultivation. Computer Applications in Biotechnology, CAB9, Nancy, France.

Ren, H. T., C. Posten, et al. (2004) A study on optimal feeding strategy for Pichi pastoris. Computer Applications in Biotechnology, CAB9, Nancy, France.

Rodriguez, J., I. Perner, et al. (2004) Simple metabolic model of Saccharomyces cerevisiae in fed-batch culture to study the cellular nitrogen uptake. Computer Applications in Biotechnology, CAB9, Nancy, France.

2003

Csögor, Z., P. Fleck, et al. (2003) Simulation of Photo-Bioprocesses. euro-biotech: 38-39.

Fleck, P. and C. Posten (2003) Mathematische Modellierung der einzelligen Mikroalge Porphyridium pupureum. Chemie Ingenieur Technik 75(1-2): 139-142.

Hofmann, R. and C. Posten (2003) Improvement of dead-end filtration of biopolymers with pressure electrofiltration. Chemical Engineering Science 58(17): 3847-3858.

Hofmann, R. and C. Posten (2003) Pressure Electrofiltration of Biopolymers in a New Developed Chamber Filter Plate. Filtech Europa 2003, Düsseldorf.

Kiessling, B. and C. Posten (2003) Molekulardynamische Simulation zu Verhalten und Wirkung polycyclischer aromatischer Kohlenwasserstoffe (PAK) in Phospholipid-Membranen. Chemie Ingenieur Technik 75(GVC Jahrestagung 2003): 1080.

Mironescu, M., I. D. Mironescu, et al. (2003) Influence of cultivation media on halobacteria I. Growth and biomass formation. Acta Universitatis Cibiensis 7: 17-24.

Mironescu, M., I. D. Mironescu, et al. (2003) Influence of cultivation media on halobacteria II. Polysaccharide production. Acta Universitatis Cibiensis 7: 25-32.

Perner, I. and C. Posten (2003) CFD Optimisation of a Plate Photobioreactor used for cultivation of microalgae. Engineering in Life Sciences 3: 287-291.

2002

Hofmann, R. and C. Posten (2002) Pressure Electrofiltration in a new designed chamber filter plate - a highly promising method for the biopolymer recovery. Proc. International Conference on Emerging Solid/Liquid Separation Technologies, ICEST 2002, Compiègne, France.

Hofmann, R. and C. Posten (2002) Biopolymer Recovery with the Pressure Electrofiltration and Determination of the Biopolymer Quality by MAS-NMR and FT-IR Techniques. Engineering in Life Sciences 2: 304-311.

Perner, I., C. Posten, et al. (2002) CFD gestützte Optimierung eines Platten-Photobioreaktors zur Kultivierung von Mikroalgen. Chemie Ingenieur Technik 74(6): 865-869.

Posten, C. (2002) Biological Aspects in Bioseparation. Study for IFPRI. Tampa, Fl.: 63.

2001

Berg, M., K. Undisz, et al. (2001) Evaluation of liquid handling conditions in microplates. Journal of Biomolecular Screening 6(1): 47-56.

Csögör, Z., B. Kiessling, et al. (2001) Growth and product formation of Porphyridium purpureum. Journal of Applied Phycology 13(4): 317-324.

Csögör, Z., M. Herrenbauer, et al. (2001) Light distribution in a novel photobioreactor - modelling for optimisation. Journal of Applied Phycology 13(4): 325-333.

Csögör, Z. and C. Posten (2001) Biologische Wirkungen von Holzsaft aus Buche und Fichte. Chemie Ingenieur Technik 73(4): 389-393.

Desplancq, D., B. Kieffer, et al. (2001) Cost-effective and uniform C-13- and N-15-labeling of the 24-kDa N-terminal domain of the Escherichia coli gyrase B by overexpression in the photoautotrophic cyanobacterium Anabaena sp PCC 7120. Protein Expression and Purification 23(1): 207-217.

Herrenbauer, M. and P. D. Tieleman (2001) Molecular Modelling of Diffusional Motion and Transfer of Pyrene in Lipid Membrane. 8th International Conference in Computer Applications in Biotechnology, CAB8, Québec, Canada.

Hoffmann, F., C. Posten, et al. (2001) Kinetic model of in vivo folding and inclusion body formation in recombinant Escherichia coli. Biotechnology and Bioengineering 72(3): 315-322.

Hofmann, R., K. Weber, et al. (2001) Presselektrofiltration - eine vielversprechende Methode bei der Bioseparation. Chemie Ingenieur Technik 73(9): 1218-1224.

Hofmann, R., K. Weber, et al. (2001) Pressure Electrofiltration: A Useful Tool In Bioseparation. Science & Technology of Filtration and Separation, Tampa, Florida, AFS.

Hofmann, R., K. Weber, et al. (2001) Electrofiltration as a new tool for biopolymer recovery. Filtech Europa 2001, Düsseldorf, Germany.

Perner, I., C. Posten, et al. (2001) Modelling of a Plate-Photobioreactor using CFD. 8th International Conference in Computer Applications in Biotechnology, CAB8, Québec, Canada.

Posten, C. and C. Alles (2001) Finding New Ways to Separate BioParticles. Science & Technology of Filtration and Separations, Tampa, Florida, AFS.

Schmitt, D., A. Müller, et al. (2001) The adsorption kinetics of metal ions onto different microalgae and siliceous earth. Water Research 35(3): 779-785.

2000

Berg, M., K. Undisz, et al. (2000) Miniaturization of a functional transcription assay in yeast (human progesterone receptor) in the 384-and 1536-well plate format. Journal of Biomolecular Screening 5(2): 71-76.

Herrenbauer, M. and C. Posten (2000) Biosorption von polycyclischen aromatischen Kohlenwasserstoffen an Mikroorganismen und Zellmembranen. Chemie Ingenieur Technik 72: 1107-1108.

Posten, C. and U. Rinas (2000) Control strategies for high-cell-density cultivation of Escherichia coli. Bioreaction Engineering - Modeling and Control. K. Schügerl. Heidelberg, Springer-Verlag: 374-390.

1999

Csögör, Z., M. Herrenbauer, et al. (1999) Design of a photo-bioreactor for modelling purposes. Chemical Engineering and Processing 38(4-6): 517-523.

Csögör, Z., D. Melgar, et al. (1999) Production and particle characterization of the frustules of Cyclotella cryptica in comparison with siliceous earth. Journal of Biotechnology 70(1-3): 71-75.

Patents

Posten, C., Herrenbauer, M., Weber, K., Hofmann, R. (2003) Electrofiltration of Biopolymers. European Patent No. EP1351994
Gruenberg, M., Posten, C., Rueckel, M. (2002) Optimisation of fermentation processes. European Patent No. EP1201746

Herrenbauer, M., Z. Csögör, et al. (1999) Stirred Draft Tube Photo-Bioreactor for Modelling of Growth and Product Formation by Microalgae. 14th IFAC World Congress, Bejing, PR China.